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In the History of the Bismarck Family, the Bismarck Curse are a group of infections that only affect the Southern Bismarcks who live in the Southern United States, the infections were originated from their deformed inbred ancestor who was known by her community as "Ellie the Witch" (1890-1932), because of her deformed face and other body features.

Jonathan Saint Nicholas Bismarck XXVIII, one of Ellie's great-grandson, has some infections originated from her through the progressing of the growth of the Southern Bismarck family tree from World War II, to the 21st Century after her death in 1932.